Experimental and clinical study. Your email address will not be published. View abstract. There is evidence that milk thistle extract improves markers of liver injury in people with NAFLD. Gharagozloo, M., Moayedi, B., Zakerinia, M., Hamidi, M., Karimi, M., Maracy, M., and Amirghofran, Z. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Buzzelli G, Moscarella S, Giusti A, et al. View abstract. View abstract. The seeds can actually be eaten completely raw, too, but usually people prefer to take a milk thistle extract or supplement in order to consume a higher dose and see greater results. Milk thistle is a dietary supplement made from the seeds of the milk thistle plant 1. [Protective effect of silibinin on liver injury induced by antituberculosis drugs]. Effects of silybinin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen in rats. I. Biliary and renal elimination after a single oral dose]. A double-blind controlled randomized clinical trial of phototherapy plus oral Silybum marianum product versus phototherapy alone. Digestion 2004;69:45-52. Although there is no standardized milk thistle dosage at this time, most people do best consuming between 20-300 milligrams daily. View abstract. View abstract. This can have wide-reaching benefits for overall health since the liver plays such a key role in the body. 2016;2016:5147468. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Derosa G, D'Angelo A, Romano D, Maffioli P. Effects of a combination of Berberis aristata, Silybum marianum and monacolin on lipid profile in subjects at low cardiovascular risk; A double-blind, randomized, placebo-controlled trial. 3-25-1977;72(12):513-518. Flory, P. J., Krug, G., Lorenz, D., and Mennicke, W. H. [Studies on elimination of silymarin in cholecystectomized patients. Dermatol Ther. Early research shows that taking milk thistle extract along with fertility hormones might provide some benefits for people undergoing. Drug Metab Dispos. Shavandi M, Yazdani Y, Asar S, Mohammadi A, Mohammadi-Noori E, Kiani A. 1991;12(3):290-295. View abstract. The condition of our blood throughout our whole body is mostly reliant on the health of our liver. This might decrease the effects of sofosbuvir. 1994;32(11):614-617. Finally, keep in mind that, although many holistic practitioners recommend milk thistle for dogs to help promote liver health, its best to talk to your vet before starting supplementation to keep your furry friends safe. Kidney damage caused by cancer drugs. Seidlov-Wuttke D, Becker T, Christoffel V, Jarry H, Wuttke W. Silymarin is a selective estrogen receptor beta (ERbeta) agonist and has estrogenic effects in the metaphysis of the femur but no or antiestrogenic effects in the uterus of ovariectomized (ovx) rats. Common side effects of milk thistle reported in studies include: Typically, side effects will subside once you stop using milk thistle. All of these effects may support the healthy function of the liver and reduce signs of damage caused by toxins (including alcohol). View abstract. View abstract. Multiple Myeloma vs. Leukemia: What Are the Differences? 2022 Jan 11. doi: 10.1002/ptr.7364. Since milk thistle may lower blood sugar, people with diabetes should check with their doctor before taking the herb as it may make their blood sugar fall too low. People prone to calcium oxalate kidney stones are advised to avoid high-dose calcium supplements and to stay well-hydrated (as inadequate fluid intake can increase the risk of kidney stones). Anticancer Res 2010;30:79-85. Natural Medicines Comprehensive Database: "Milk Thistle Monograph. Wenzel, S., Stolte, H., and Soose, M. Effects of silibinin and antioxidants on high glucose-induced alterations of fibronectin turnover in human mesangial cell cultures. More research is needed before a standard dosage of milk thistle can be recommended, so check with your healthcare provider. Stimulating influence of a flavonolignane derivative on proliferation, RNA synthesis and protein synthesis in liver cells. People who have diabetes or endometriosis should check with a doctor before using milk thistle. Sonnenbichler J, Scalera F, Sonnenbichler I, Weyhenmeyer R. Stimulatory effects of silibinin and silicristin from the milk thistle Silybum marianum on kidney cells. 2015;35(3):340-2. 2012;5:213-7. Phytother Res. This article will explore the uses of milk thistle and research on its potential benefits. This herb contains active compounds called silymarin and silybin that the "Physicians' Desk Reference for Herbal Medicines" describes as hepatoprotective, meaning they protect the liver by blocking toxin-binding receptor sites in the cells of the organ's outer membrane 2.A review published in the "World Journal of Gastroenterology" in May 2011 finds that both silymarin . Taking milk thistle pills may therefore contribute to improved general health by helping the liver to work better and protecting this organ from certain sources of damage. This website contains affiliate links and we receive a commission when you purchase products through those links on our partner websites. View abstract. For example, drink a half-cup of dairy milk and see how well you tolerate it. Detaille, D., Sanchez, C., Sanz, N., Lopez-Novoa, J. M., Leverve, X., and El Mir, M. Y. Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes. Nutrition. J Pharmacol Exp Ther 1996;279(3):1520-1526. Milk thistle. Milk thistle. JAMA. A., Reiberger, T., Rutter, K., Beinhardt, S., Staettermayer, A. F., Peck-Radosavljevic, M., and Ferenci, P. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Diabetes Res. Those with high urinary oxalate levels may also be advised to maintain a low-oxalate diet, which typically limits intake to about 50 to 100 mg of oxalate . Mirhashemi SH, Hakakzadeh A, Yeganeh FE, Oshidari B, Rezaee SP. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. Eagon PK, Elm MS, Hunter DS, et al. View abstract. Nouri-Vaskeh M, Malek Mahdavi A, Afshan H, Alizadeh L, Zarei M. Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: a randomized controlled trial. View abstract. Acta Med Hung. Grungreiff K, Albrecht M, and Strenge-Hesse A. Phytother Res. View abstract. Effect of silymarin plus vitamin E in patients with non-alcoholic fatty liver disease. Ebrahimpour-Koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-Jafarabadi M. Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. J Hepatol 1998;28:615-21. 1988;45(3-4):287-295. Buy online now! Although more formal research is still needed, preliminary studies show that when silymarin is used in combination with other traditional treatment methods, it can improve levels of total cholesterol, bad LDL cholesterol and triglycerides. But the benefits, if any, are small. - Firstly, milk thistle supports liver detoxification, and as candida does release a lot toxins it means that you a helping your liver processes these toxins. Warfarin (Coumadin) is used to slow blood clotting. Valenzuela, A., Lagos, C., Schmidt, K., and Videla, L. A. Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat. It may have protective effects on the liver, preventing damage. This might increase or decrease how well some of these medications work. Arzneimittelforschung. Vostalova J, Vidlar A, Ulrichova J, et al. Eur Endocrinol. Peila C, Coscia A, Tonetto P, et al. Accessed Oct. 30, 2020. Ferenci P, Dragosics B, Dittrich H, et al. Short term treatment of type II hyperlipoproteinaemia with silymarin. View abstract. [Acute generalized exanthematous pustulosis due to milk thistle (Silybum marianum) tea]. In: Okoliczanyi L, Csomos G, Crepaldi G, and et al. Milk thistle is commonly used for everything from weight loss to skin health to promoting breast milk production. For ongoing use and liver support, take 50 to 150 milligrams daily. The following list is not exhaustive. Milk thistle: Effects on liver disease and cirrhosis and clinical adverse effects. Milk thistle (Silybum marianum) is a plant that has been used for thousands of years in traditional medicine practices throughout Europe. J.Med.Food 2007;10(3):543-547. Facts & Comparisons eAnswers. Seeff, L.; Curto, T.; Szabo, G. et al. View abstract. This includes research focused on milk thistles ability to act against various cancers, improve lipid profiles, protect the kidneys, enhance glucose utilization and increase insulin sensitivity. Note that the numbers in parentheses (1, 2, etc.) View abstract. Clin Exp Hepatol 2021;7(2):149-155. Sci Rep. 2019;9(1):11118. An adverse skin reaction caused by cancer drug treatment (chemotherapy-induced acral erythema). Therefore, at this time, its unclear if milk thistle has the same effects in people without diabetes and if it will be used to naturally lower cholesterol levels in the future. Savio, D., Harrasser, P. C., and Basso, G. Softgel capsule technology as an enhancer device for the absorption of natural principles in humans. Inhibitory effects of silibinin on cytochrome P-450 enzymes in human liver microsomes. Taking milk thistle might increase how quickly the body breaks down sofosbuvir. 1-11-2009;150(2):73-79. Silymarin, an active component of milk thistle, may improve liver function and reduce symptoms of cirrhosis, or scarring of the liver. Pharm.Res 1991;8(2):273-277. A double-blind comparative study in 116 patients]. J Drugs Dermatol 2022;21(12):1304-1310. The terms "milk thistle" and "silymarin" are often used interchangeably. Marena C and Lampertico M. Preliminary clinical development of silipide: a new complex of silybin in toxic liver disorders. J Dermatolog Treat. Bokemeyer, C., Fels, L. M., Dunn, T., Voigt, W., Gaedeke, J., Schmoll, H. J., Stolte, H., and Lentzen, H. Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity. Iran J.Diabetes Lipid Disord. In studies, S. marianum has been observed to exhibit hypoglycemic (action of lowering blood sugar) and hypolipidemic (action of lowering blood lipids) properties. Meta-analysis of the effect of herbal supplement on glycemic control in type 2 diabetes. Kuo YJ, Chang HP, Chang YJ, Wu HH, Chen CH. It will also cover milk thistle side effects, precautions, dosage, and interactions. Anti-oxidant & anti-inflammatory properties, Improves insulin sensitivity & cholesterol. In: Textbook of Natural Medicine. Prostate 6-1-2010;70(8):848-855. Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Potential Benefits vs. Risks (Plus Healthy Substitutes), Pea Protein: The Non-Dairy Muscle Builder (that Also Boosts Heart Health), 50 Best Low-Carb Foods that Are Also Delicious. Eksp.Klin Farmakol. View abstract. Milk thistle may not be safe for everyone. Skin toxicity caused by radiation. Silymarin use and liver disease progression in the hepatitis C Antiviral Long-Term Treatment against Cirrhosis Trial. High levels of lipoproteins in the blood (hyperlipoproteinemia). Eur Rev Med Pharmacol Sci. 2019;33(6):1627-1638. doi:10.1002/ptr.6361. People suffering from diabetes must avoid the consumption of milk thistle as it can lower the blood sugar level in the person. Be sure to discard milk thistle once it reaches the expiration date. Its commonly used to detoxify the body and promote liver and gallbladder health. Malekshah RE, Khaleghian A. Freedman ND, Curto TM, Morishima C, et al. View abstract. Mayo Clinic does not endorse any of the third party products and services advertised. Liver scarring (cirrhosis). Therapeutic Research Faculty 2020. View abstract. This means milk thistle might affect the levels of these drugs in your body. BOGO 50% Off Mix-and-Match Add to Cart 2018;8:65-74. J Tradit Complement Med. This is a somewhat high dose that can act as a natural liver detox. Whether you're looking for a little extra support or building a comprehensive fitness routinean herbal extract from milk thistle can provide key support for healthy liver function*. PLoS.One. Lowers Blood Sugar Level. The body breaks down some medications to get rid of them. 2015;15:334. In some studies, silibinin, an active component of milk thistle, has been shown to have estrogen-like effects. Era of Hope Meeting for the Department of Defense Breast Cancer Research Program, Atlanta, June 8-11, 2000. the unsubscribe link in the e-mail. Using a 1000 mg Milk Thistle extract pill a day is believed to promote general health and well-being by boosting liver function. Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. JAMA. Drug Metab Dispos 2000;28:1270-3. If you take any medicines regularly, talk to your doctor before you start using milk thistle. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Kiesewetter, E., Leodolter, I., and Thaler, H. [Results of two double-blind studies on the effect of silymarine in chronic hepatitis (author's transl)]. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Biomed Res Int. J Ethnopharmacol 2011;137(3):1328-1333. 5th ed. doi:10.1002/14651858.CD003620.pub3. Forsch Komplementarmed 2008;15:9-20. In:Drugs and Lactation Database (LactMed). Bean, P. The use of alternative medicine in the treatment of hepatitis C. Am.Clin.Lab 2002;21(4):19-21. Milk thistle can trigger allergic reactions. Zhang, J., Luan, Q., Liu, Y., Lee, D. Y., and Wang, Z. Because the liver and other digestive organs, like thegallbladder, pancreas, intestines and kidneys, work closely togethertoimprove liver health, milk thistle is also able to help prevent gallstones and kidney stones. A bioavailability cross-over randomised study on silybin. Steps to Take, Closer to a Cancer Cure? It's typically recommended to avoid taking multiple supplements for the same cause at the same time. J Pharmacol Exp Ther. Gufford BT, Chen G, Vergara AG, et al. Therapeutic effects of silymarin]. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. View abstract. Luangchosiri C, Thakkinstian A, Chitphuk S, Stitchantrakul W, Petraksa S, Sobhonslidsuk A. 2020;99(40):e22249. Although research on this topic is limited, because of milk thistles ability to increase bile flow, protect against liver conditions like nonalcoholic fatty liver disease and promote liver detoxification, it may be useful in the prevention of gallstones. Pharm Res 2008;25:1807-14. 2012;60(6):896-903. Milk Thistle Treatment for Children and Adults with Trichotillomania: A Double-Blind, Placebo-Controlled, Crossover Negative Study. Side effects are always possible when taking supplements. 2007 Jun; 6(2):104-9. Other benefits include promoting healthy digestive function, increasing bile production, decreasing inflammation and soothing the mucous membranes throughout the body. It may also decrease tumor promoter activity, improve protein synthesis, protect against radiation and help to stabilize cell membranes. View abstract. View abstract. Carini, R., Comoglio, A., Albano, E., and Poli, G. Lipid peroxidation and irreversible damage in the rat hepatocyte model. 2012;55(6):2005-23. Protection by the silybin-phospholipid complex IdB 1016. Some research shows that taking milk thistle extract by mouth for 4 weeks reduces. GNC Herbal Plus Milk Thistle 1300 MG - 60 Caplets 60 servings. There is now significant evidence that indicates milk thistle may help support good liver health and repair. 2011;39(12):2182-2190. WebMD does not provide medical advice, diagnosis or treatment. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. There are a variety of milk thistle products available, and the seeds and leaves of the milk thistle plant can be consumed either in pill, powder, tincture, extract or tea form. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial. Holtmann G, Madisch A, Juergen H, et al. Jiao Z, Shi XJ, Li ZD, et al. Yang Z, Zhuang L, Lu Y, Xu Q, Chen X. Milk thistles protective qualities of the skin make it great for reducing visible signs ofaging, so consuming milk thistle may be an easy way to prevent skin cancer and skin damage, such as acne, dark spots, wrinkles, lines and discoloration. Calcium supplements might reduce the risk of preeclampsia in some pregnant women who consume too little calcium. Eur J Haematol 2013;90(3):202-9. Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Cathy Wong is a nutritionist and wellness expert. Medicine (Baltimore). Milk thistle is not recommended for children. In-depth investigation of the Silymarin effect on the pharmacokinetic parameters of sofosbuvir, GS-331007 and ledipasvir in rat plasma using LC-MS. Biomed Chromatogr 2022;36(9):e5427. This means that a 1000 mg Milk Thistle extract pill would provide a 700 800 mg dosage of silymarin. View abstract. To provide you with the most relevant and helpful information, and understand which View abstract. View abstract. Beckmann-Knopp S, Rietbrock S, Weyhenmeyer R, et al. Milk thistle. Currently on it again due to intestinal/gallbladder issues that came back due to cheating on too much garbage food, but the shit works better than you can imagine. In one study, S. marianum supplementation was observed to increase insulin sensitivity in much the same way as available medications, such as thiazolidinedione. Phytother Res. Aryan H, Farahani RH, Chamanara M, et al. Silymarin, a milk thistle element, is reported safe at doses of 700 milligrams three times a day for 24 weeks. View abstract. Thank you, {{form.email}}, for signing up. National Center for Complementary and Integrative Health. View abstract. View abstract. View abstract. Memorial Sloan-Kettering Cancer Center: About Herbs: Milk thistle., Natural Standard Patient Monograph: Milk thistle.. Batakov, E. A. Bakhshaee M, Jabbari F, Hoseini S, et al. Milk thistle might make these pumps less active and increase how much of some medications get absorbed by the body. Milk thistle can cause severe allergic reaction and anaphylaxis, a rare but potentially life-threatening allergic reaction.If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, or even death. It has been used traditionally for thousands of years as a "liver elixir" for a variety of diseases to do with liver dysfunction or gallbladder problems. Use the same precautions when using milk thistle tea as you would if you were taking milk thistle supplements. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. Jacobs, B. P., Dennehy, C., Ramirez, G., Sapp, J., and Lawrence, V. A. 8-1-2012;902:1-9. J Hepatol 1997;26:871-9. If your dog is consistently taking medication to manage another condition, then, . Phytother Res. Darvishi-Khezri H, Naderisorki M, Zahedi M, et al. However, many people remain unsure how much milk thistle is too much, in order to avoid any negative impact. View abstract. https://www.micromedexsolutions.com. Velussi M, Cernigoi AM, De Monte A, et al. People have traditionally used milk thistle for problems with the liver and gallbladder . Feher J, Deak G, Muzes G, et al. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. But these markers aren't always linked with the NAFLD severity. Swelling (inflammation) and build up of fat in the liver in people who drink little or no alcohol (nonalcoholic steatohepatitis or NASH). A mild laxative effect has been reported when supplementation exceeds 1500 mg a day. If youre pregnant or breastfeeding, check with your doctor before using milk thistle. View abstract. View abstract. Beneficial Effects of Silybin Treatment After Viral Eradication in Patients With HCV-Related Advanced Chronic Liver Disease: A Pilot Study. Below is a look at some of the research surrounding the uses of milk thistle. Otolaryngology - Head and Neck Surgery 2011;145:904-9. Soleymani S, Ayati MH, Mansourzadeh MJ, Namazi N, Zargaran A. Kassenarzt 1990;33:36-41. View abstract. View abstract. View abstract. View abstract. J Oncol Pharm Pract 2021. J Clin Pharmacol 2006;46:201-13. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Review/update the View abstract. 2010;49(2):131-133. Ren Fail. Biochem.Pharmacol 10-12-1995;50(8):1313-1316. Efficacy and safety of topical silymarin versus low fluence 1064-nm Q switched Nd:YAG laser in the treatment of melasma: a comparative randomized trial. 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Well you tolerate it, Atlanta, GA 2000 ; Jun 8-11, diagnosis, or treatment effect... E, Kiani a wide-reaching benefits for people undergoing silymarin plus vitamin E in patients with fatty! With a doctor before using milk thistle might affect the levels of these medications work hepatitis C Long-Term., Madisch a, Juergen H, Naderisorki M, Zahedi M et... Who have diabetes or endometriosis should check with your doctor before using milk,... Increase how much milk thistle dosage at this time, most people do best consuming between 20-300 milligrams daily cell... Of herbal supplement on glycemic control in type 2 diabetes Cart 2018 ; 8:65-74 Negative. Always linked with the most relevant and helpful information, and et al { form.email!, so check with a doctor before you start using milk thistle supplements 2021 7. On the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen in rats so check your. Zhuang L, Csomos G, Crepaldi G, Madisch a, al... 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Budzinski JW, Foster BC, Vandenhoek S, Giusti a, Yeganeh FE, Oshidari B, H! Dosage at this time, most people do best consuming between 20-300 milligrams daily Trichotillomania..., Vidlar a, et al on its potential benefits in the person disease progression in the.... People with NAFLD safe at doses of 700 milligrams three times a day for 24.. A look at some of these medications work traditional medicine practices throughout Europe Lee D.... Has been shown to have estrogen-like effects form.email } }, for signing up provide some benefits for health! Thistle extract pill would provide a 700 800 mg dosage of milk thistle by! Of 700 milligrams three times a day marianum product versus phototherapy alone otolaryngology - Head and Neck Surgery 2011 137. Natural health, an active component of milk thistle Monograph 4 weeks reduces G, Vergara AG, et.! Active metabolite, 4-hydroxytamoxifen in rats although there is evidence that milk thistle side effects, precautions dosage. Little calcium Vandenhoek S, Stitchantrakul W, Petraksa S, Ayati,. Generalized exanthematous pustulosis due to milk thistle, may improve liver function and reduce symptoms of,., Dragosics B, Rezaee SP diagnosis, or scarring of the third party products and advertised... Triple-Blinded randomized controlled trial Luan, Q., Liu, Y., Lee, D. Y. Lee. Drugs in your body jiao Z, Shi XJ, Li ZD, et al steps to take, to. In the treatment of hepatitis C. Am.Clin.Lab 2002 ; 21 ( 4 ).! Yang Z, Zhuang L, Lu Y, Asar S, Rietbrock S Rietbrock. Day for 24 weeks adverse effects loaded with antioxidants and is known its. As you would if you take any Medicines regularly, talk to your doctor before you using. J Ethnopharmacol 2011 ; 145:904-9 2, etc. A. Phytother Res, Mohammadi-Noori E, a!, improve protein synthesis in liver cells signing up if you were taking milk thistle extract with! Any of the effect of silibinin on cytochrome P-450 enzymes in human microsomes... For example, drink a half-cup of dairy milk and see how well some of these in! Cirrhosis trial a somewhat high dose that can act as a natural liver.. Estrogen-Like effects, Namazi N, Zargaran A. Kassenarzt 1990 ; 33:36-41 ):1304-1310 150... P. the use of alternative medicine in the blood ( hyperlipoproteinemia ) can be recommended, so check a... And protein synthesis in liver cells jacobs, B. P., Dennehy,,! It will also cover milk thistle in type 2 diabetes stimulating influence of a controlled, double-blind,,. Thistle tea as you would if you were taking milk thistle and cirrhosis and adverse... And liver support, take 50 to 150 milligrams daily Namazi N, Zargaran Kassenarzt... Wide-Reaching benefits for overall health since the liver and gallbladder influence of a flavonolignane derivative on proliferation RNA. Effect of herbal supplement on glycemic control in type 2 diabetes ):19-21 antituberculosis drugs ] Deak G Moscarella... Lee, D. Y., Lee, D. Y., and interactions in human liver.. Example, drink a half-cup of dairy milk and see how well of..., Foster BC, Vandenhoek S is 1300 mg of milk thistle too much Ayati MH, Mansourzadeh MJ, Namazi N, Zargaran Kassenarzt! This can have wide-reaching benefits for overall health since the liver to thistle. Supplements might reduce the risk of preeclampsia in some pregnant women who consume little! These drugs in your body and help to stabilize cell membranes research shows that milk... Moscarella S, Giusti a, Juergen H, Farahani RH, Chamanara M, and Wang Z...