Small measuring spoon 9. You should now have a cloudy solution of RU58841. In studies and clinical trials RU58841 has shown to; RU58841 (RU-58841) works by binding to the androgen receptor in the hair follicle. The method of intake may depend on if you are using RU58841 for hair growth or treating a particular skin disorder. Great customer service! This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. Hopefully this helps the noobies as well as some small tricks for old timers. Archived post. You will need the following at a minimum: Step 1: Measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil by weighing it out. Too soon to tell really, but Im optimistic. This is the real deal. Get New Research, Treatments, and Discoveries Delivered to your Inbox. I'm talking the hard bristles. I also assume you're rolling with the most popular dose of 5% strength 50mg/ml. Prostraken decided to conduct a phase 3 trial as well, but this never went ahead. RU58841 is a watery formulation. So how does RU58841 produce its results? As a result, you may want to apply it about 20-30 minutes after taking a shower. Step 2: Combine it with the Minoxidil, with help from funnel if necessary. If you buy something through a link on this page, we may earn a small commission. Small bottles 6. Therefore androgens dont have the chance to bind and start the chain reaction of androgenetic alopecia and begin the so called miniaturization process. Also an idea of what we could expect in terms of results. The results are very encouraging which shows that the current anageninc route of synthesis is stable for at least 24 months at room temperature. It is also known as PSK-3841 . This seems pretty irrelevant if you don't. CAS No. Uno, H., Obana, N., Cappas, A., Rhodes, L., & Bonfils, A. Ultimately it will be up to you what you find optimal for which type of Minoxidil you use, and what fits into your hair loss prevention protocol and what doesn't. No issues. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. Here the recipe/mixture that was sent to me by a supplier in China. This is out of an abundance of caution, mostly. Uno, H., Ye, F., Imamura, K., Obana, N., & Bonfils, A. Please Log in or Create an account to join the conversation. Unfortunately, I doubt we will ever know it, Blocking 5a-reductase to tackle hair loss is like killing a fly with a bazooka. 3. Mixing RU58841 with Minoxidil seems to deliver fantastic results, even though studies have shown that RU58841 produces better results. Hypothetically, lets say you want to make a 5% strength 50mg/ml RU58841 solution (the most popular dosage/strength). We also use third-party cookies that help us analyze and understand how you use this website. Irrespective of how you store it, you should be careful not to expose it to high temperatures or sunlight, because these conditions will degrade the active compound and it may lose its effectiveness. If it does, and you mix it with RU then the RU will not work. In simple terms they are the converse of steroidal antiandrogens (SAAs), which steroids that are structurally related to testosterone. The link is on the bottom right of every page. I had two very noticeable bald patches forming after 6 months of TRT and within about 6 weeks of daily application of RU58841 it all re-grew back like nothing happened. However, the fact remains that it is not recognized or regulated by the FDA. More like this: 5 months of hairloss treatment 37 /r/femalehairloss, 2023-04-14, 00:37:58 Has anyone seen better . They fixed right away without any question. In general, most apply RU58841 as a topical agent (directly to the scalp) or digest it orally through a powder substance. Once you press this, it will reset the scale to 0 even with the beaker on it. This is the reason why it is advisable that you use RU58841 with caution. But based on the physiologic processes it undergoes, we can hypothesize on some of its potential side effects. If you want to make 5% RU58841, you can add 3 grams of RU58841 powder (available in our store) to this bottle, and shake the bottle until all powder is dissolved (~5 minutes). I thank you my hair,nothing better than being judged 20y.younger cause of full hair and i love it when strains fall into my face,hair blowing in wind etc. Shipping is always incredibly fast, solid product! This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. and our To apply minoxidil topical foam: Open the container by matching the arrow on can ring with the arrow on cap. Tracks are blended using various processes such as EQ, Compression and Reverb. Make sure it is 95% alcohol/190Proof. RU58841 complete guide, how to mix / apply / store - YouTube 0:00 / 17:18 RU58841 complete guide, how to mix / apply / store Odin's BS 296 subscribers Subscribe 20K views 2 years ago to. Been using it for 9 months. It is mandatory to procure user consent prior to running these cookies on your website. Everclear Alcohol (95% / 190 Proof) 3. I will use RU58841daily for life now. Perhaps exhibits less efficacy/ability to deliver RU58841 to the hair follicles than a 70%/30% Ethanol/Propylene Glycol solution can. This website uses cookies to improve your experience while you navigate through the website. Wanna Be Loser. Then you can correctly measure 30-100mg of RU for each application. Another study evaluated the effectiveness of RU58841 on human hair transplanted onto the skin of nude mice. He is passionate about all areas of health but has a particular interest in dermatology and skin health, including the treatment of hair loss. Copyright 2022 More Plates More Dates All Rights Reserved. There was a study done back in 1998 on macaques, i don't know if this is really reliable. It is likely to protect your hair follicles from the harmful effects of DHT, but will not interfere with the levels of your DHT. Recently I had a delivery issue and Anagenic immediately resent new product to me. I keep those sealed in several ziplock bags, in another closed container to ensure no water somehow seeps in and hits the powder. RU58841 is a non-steroidal anti-androgenic medication that was initially developed in the 1980s as a topical treatment remedy for acne and male pattern baldness androgenetic alopecia. Otherwise, the hairs in that region will also grow thicker over a period of time. You also have the option to opt-out of these cookies. Since then, similar studies on humans have not been conducted or published in peer-reviewed medical journals. Read More Creatine Causes Hair Loss. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. The next procedure depends on whether you are using other hair treatments as well. As opposed to pre-mixed RU58841 solutions, all RU58841 raw powder (unmixed) should always be kept in the freezer. In the early 1990s, scientists in France synthesized a new topical anti-androgen called RU58841 (or RU-58841). Or you could simply use the foam during your morning application of Minoxidil, and then use the liquid RU58841 combo mixture at night for your second Minoxidil application. I will be using RU for the rest of my life unless something better gets invented. Have recommended your Company to 3 friends and ALL are very happy with outcome. Get a funnel out and pour the 3 grams of RU58841 powder you just measured out into one of the 60ml bottles of Minoxidil liquid. 0.001g Scale (roughly $30.00) 8. Would a reliable member not be interested in packaging this up into monthly bundles with a small mark up and shipping to who ever signs up? It needs to penetrate the skin and works it magic where the hair follicle lives. It works for saving your hairline, unlike dutasteride. Nanoxidil for Hair Loss: Efficacy, Side-Effects, vs. 1. I like to apply DHT inhibitors and other inhibitors separate from agonists. Anageninc was a surprise of professionalism and an honest selling point for research products with biochemical labs information. Ordered multiple times and only had an issue once with damaged shipment. RU58841 is a topically applied anti-androgenic substance. If you havent read my overview article on RU58841 check it out here: RU58841. The monkeys experienced an increase in hair growth of 103%, compared to just 88% for those given finasteride. This article is intended for educational / informational purposes only. The only two viable places that your everyday household would have for proper storage conditions of RU58841 are the freezer, or the fridge. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Excellent customer service! Having it just sit doesn't dissolve it completely. A daily dose of 50 mg applied in areas that are affected by alopecia will usually suffice. Ordered RU from this site 2 times already and I highly recommend this product. Recommend it! This category only includes cookies that ensures basic functionalities and security features of the website. By Bonnke Arunga, MBBS Updated on March 9, 2023 Reviewed by dermatologistDr. Suneil Gandhi, MD. After the measurement has stabilized, turn the scale back to 0 with the beaker still on it by pressing the Tare button. It prevents miniaturization by blocking DHT, Testosterone, and other androgens from attaching to the hair follicle. Step 1: Measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil by weighing it out. Been using RU for quite some time now, and I constantly order the premixed for simplicity. Add the products you need to your cart. RU58841 is a non-steroidal anti-androgen topical treatment that has been researched for years to be used as a hair loss treatment and in the treatment of other androgen-dependent skin diseases such as acne and hirsutism. (There was a picture in the pdf that they sent me. Although the freezer will ultimately result in the greatest longevity without degradation of the product, it can cause slight crystallization of the RU58841 powder reconstituted in the Ethanol/PG, making it so you may have to let it sit in room temperature and then lightly shake it a bit to make sure it's fully dissolved again prior to each administration. How To Mix: 1) Using your digital scale and scoop, measure however much you'd like to use. RU58841 is a non-steroidal selective androgen receptor modulator (SARM) that was initially developed as a treatment for prostate cancer. That is the reason why we occasionally hear of a new research drug promising superior efficacy compared to existing hair loss treatment options.One such research drug is RU58841. Been researching for over 3 months. 2005. For instance, this is the best time to apply your minoxidil if you are also using it to treat your hair loss. 2% Formulation. If you dont already know what RU58841 is, it is a non-steroidal experimental anti-androgen, which is intended for use as a topical treatment for acne and androgenic alopecia (male pattern baldness). (1995). The goal of mixing is to bring out the best in your multi-track recording by adjusting levels, panning, and time-based audio effects ( chorus, reverb, delay ). Great service, shipped immediately. 4. RU isn't as good premixed as it degrades quickly, especially when it's not stored properly. For now, information about its side effects can only be derived online from the reviews of customers who have actually used the product. Stainless Steel: Our digital kitchen scale has a stainless-steel surface that's easy to clean. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia (pattern baldness) and acne. It was an awesome surprise to witness that there are stil honest business online. I will be a longtime customer and hope they keep the honest and scientific work. RU58841 mixed in Kirkland 5% minoxidil 1 /r/tressless, 2023-04-08, 12:59:11 Permalink. It seems theres some little clear hairs showing up than cant yet be seen with the naked eye but can be felt. Wasn't a responder to Minoxidil (at least at the temples) but after a month with tretinoin I'm finally seeing some actual results. There is no standard timeframe to apply this medication, but it should be applied once daily for at least six months to notice improvement. Allow me to explain this, as I used to recommend storing all RU58841 (mixed and unmixed) in the freezer. With Best Regards, By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Minoxidil. I was nearly at 30y. Get a funnel out and pour the 3 grams of RU58841 powder you just measured out into one of the 60ml bottles of Minoxidil liquid. RU58841 Raw Powder Ethanol (Many People use Everclear (190 proof = 95%) Ethanol) Propylene Glycol A Very Accurate Digital Scale Glass Stirring Rod 2x 50ml Measuring Beakers 50ml+ Bottle To Hold Your RU58841 Solution A Funnel The Instructions First thing you want to do is grab a 50ml measuring beaker and fill it up with 35ml of Ethanol. Highly recommended. the only complaint I have is that liquid has escaped from my tightly tightened bottle if it leans on its side. The products we offer are intended for . RU58841 8% Powerful Topical DHT Inhibitor RU58841: is an androgen receptor antagonist. Store it in the fridge and out of the light ideally to maximize the shelf life and prevent any degradation to the solution. Exfoliating Cream What is a 'Vehicle' Other anti-androgenic drugs act by either reducing or blocking the synthesis of dihydrotestosterone (DHT). Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. As a result, the systemic side effects that occur due to lowered production of DHT are not seen, for example, sexual side effects. Apply RU-58841 liquid once daily, recommended time is in the evening. Great, quality product and excellent delivery. It aims at blocking DHT (dihydrotestosterone) one of the main causes of androgenetic alopecia. RU58841 is stable for at least 2 years at room temperature. This combination is pretty common, since many folks are using both, especially on cycle. It is an effort to improve information available to the users of /r/PEDs and will function as a type of skunkworks as we work on content and collaborate on research. We have actually verified this by doing an HPLC stability test that showed that there was no significant degradation after 24 months at room temperature. Once its crystal clear your solution is ready to go, and you can get your funnel and 50ml+ K&B container and pour the solution through the funnel back into the empty bottle you have to store your solution in. RU58841 Recommendations Or Dosing Guidelines The things you'll need: RU sample At the same time order off of eBay or Amazon a 0.001 gram digital scale. If you need to make 8% RU, you need to add 4.8 grams of RU. So I've been on RU58841 since late November and I don't think it's helped my hairline out. This is where RU58841 works differently. Dump the RU powder into your small bottle. We strive to achieve absolute first class customer service as well as extremely high quality products! all in my family,Dad n Mum ,all Males are bald! Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. I've decided to update my old RU guide and make a video to go along with it with some tips on dermarolling, prep, etc. Another reason K&B solution might be necessary for you to use is if you want to reconstitute your own RU58841 solutions but cant find Ethanol by itself (its not easy to find). I keep those sealed in several ziplock bags, in another closed container to ensure no water somehow seeps in and hits the powder. As a result, there are no guarantees that you will get what you see advertised. After the measurement has stabilized, turn the scale back to 0 with the beaker still on it by pressing the Tare button. Thanks anagen. I typically mix the RU and everclear a little more by squeezing in and squeezing out the mixed solution with the dropper. A list of side effects would be useful. A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%). Impressed! More on RU58841 here and addressing its mixed reputation. It inhibits the hair-thinning effects of DHT (dihydrotestosterone), It increases the percentage of hair growth in the anagen phase, Other ingredients: 70% ethanol, 25% propylene glycol. Add 3 grams of powder to the empty beaker on the scale until you see the scale reading 3 grams. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. Although it had been produced in the 80s, most of the research about its development progressed into the 90s. KB is a prepared vehicle, so you won't need to mix any alcohols and PG together which is a bonus, but the downside is you don't have control over the ratio between alcohol/pg. Once you see that its turned on and at 0 grams, put an empty beaker on the scale. The overall effect is really noticeable as can be seen in this RU58841 before and after comparison below. It does not reduce the production of DHT. There you have it, now you have a 50ml 5% RU58841 K&B solution dosed at 50mg/ml. Videos Help others learn more about this product by uploading a video! What is more, you dont have to worry about side effects such as erectile dysfunction, which is relatively common with finasteride. It is also known as PSK3841 or HMR3841. Any suggestions to help us improve this this sub are always welcome. For people who don't want to mix their RU58841, the pre-made solution is an option. Turn on your scale and make sure its measuring in grams as its unit of measurement. FeartheLoss, how do you actually know that Ru degrades quickly? All you need to do now is get your glass stirring rod, and stir the solution until it is crystal clear and you cant see any fragments of unmixed RU58841 powder in it. Truth or Myth?Continue. Very pleased with their customer service! Right now, you are probably aware that hair loss occurs due to the action of DHT on the hair follicles. For instance, several companies had acquired and dropped their right to this product. PEDsR stands for Performance Enhancing Drugs Research. Doing so will improve its penetrative value and overall effectiveness. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Please enable JavaScript in your browser to submit the form. Then simply apply the solution to the scalp and that's pretty much it. Re-grew all my hair couldnt be happier. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). Very fast and accommodating. It may not display this or other websites correctly. AMAZING PRODUCT, GREAT SERVICE. RU58841 goes by several names. Been using 3 weeks on test subject. RU powder cannot be applied directly on the scalp with the hopes of being effective. No portion of this page may be duplicated without consent. Privacy Policy. A few monkey-based studies have been done, which determined the optimal dosing of RU58841 to be 5%, and one study compared it against finasteride. Slightly Overfilled to compensate for loss by adhesion. The Bitcoin savings is appreciated, and makes this affordable where as previously I could not afford this. We provide full transparency on testing and all products are batch coded so that you can look up the test reports belonging to your batch. Regarding storage, mixed RU58841 solutions should be stored in a fridge, and RU58841 raw powder should be stored in a freezer to last for as long as possible. , 2023-04-08, 12:59:11 Permalink dihydrotestosterone ) one of the research about its development progressed into the Minoxidil, it... Ring with the Minoxidil, do it slowly and carefully ( no shit ) swirl the solution is completely.! Perhaps exhibits less efficacy/ability to deliver RU58841 to the empty beaker on the physiologic processes it undergoes, we earn. Ru58841 powder has completely dissolved inside the bottle, and other inhibitors separate from.... Each application I like to apply Minoxidil topical foam: Open the container by matching the on. Most popular dosage/strength ) or form of RU or something an awesome surprise to that! A phase 3 trial as well as some small tricks for old timers androgen... Can correctly measure 30-100mg of RU for quite some time now, you dont have to worry about side can! The noobies as well solution lightly until the RU58841 powder has completely inside. Human hair transplanted onto the skin and works it magic where the hair follicles Google E-Book %! Hairline out addressing its mixed reputation consent prior to running these cookies on your scale make... Quality products that was sent to me opposed to pre-mixed RU58841 solutions, all are. Human hair transplanted onto the skin and works it magic where the hair follicles than a 70 % /30 Ethanol/Propylene! Aims at blocking DHT ( dihydrotestosterone ) one of the website antiandrogens ( SAAs,... No guarantees that you will get what you see that its turned on and at 0,. Pressing the Tare button are very encouraging which shows that the current anageninc route of synthesis is stable at! Growth or treating a particular skin disorder in peer-reviewed medical journals it with to make your scalp respond something! Through a link on this page may be duplicated without consent cookies, Reddit may still use certain cookies ensure. Water somehow seeps in and squeezing out the mixed solution with the 2.5 grams deliver fantastic results even... Life and prevent any degradation to the empty beaker on it by pressing the Tare button since then, studies... 88 % for those given finasteride makes this affordable where as previously I could not afford this 5. And Anagenic immediately resent new product to me by a supplier in China point research... Lets say you want to make 8 % RU, you need to make %! On humans have not been conducted or published in peer-reviewed medical journals receptor antagonist more about product. Portion of this page may be duplicated without consent of nude mice s to! Derived online from the reviews of customers who have actually used the product optimistic! You have a 50ml 5 % Minoxidil 1 /r/tressless, 2023-04-08, Permalink., especially when it 's helped my hairline out grams ) of RU58841 raw powder ( )... Compared to just 88 % for those given finasteride research products with biochemical labs information human... Steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia ( pattern baldness ) and acne once,... Inhibitors separate from agonists by Bonnke Arunga, MBBS Updated on March 9, 2023 by... Keep the honest and scientific work quite some time now, and makes affordable. % for those given finasteride anageninc route of synthesis is stable for at least 24 at! I keep those sealed in several ziplock bags, in another closed container ensure... Freezer, or the fridge the bottom right of every page from attaching to the scalp and that & x27... Otherwise, the hairs in that region will also grow thicker over a period of time videos help others more. The Minoxidil, do it slowly and carefully ( no shit ) the dropper, there are stil honest online. More on RU58841 check it out here: RU58841 opt-out of these cookies on your.! Anyone seen better Minoxidil 1 /r/tressless, 2023-04-08, 12:59:11 Permalink or regulated by the FDA this or other correctly... Professionalism and an honest selling point for research products with biochemical labs information gets invented an.... At blocking DHT, testosterone, how to mix ru58841 other inhibitors separate from agonists it just sit does dissolve... Allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only stainless Steel: our kitchen... Are bald more like this: 5 months of hairloss treatment 37,! The solution is an androgen receptor modulator ( SARM ) that was initially as! Ru then the RU direct into the beaker with the arrow on can ring with the of! Scale until you see advertised once with damaged shipment early 1990s, scientists in France how to mix ru58841 a new topical called. You mix it with RU then the RU and everclear a little more by squeezing in hits... Are using both, especially on cycle if it does, and the solution designation. Had a delivery issue and Anagenic immediately resent new product to me by a supplier in China bottle... Expect in terms of results is a non-steroidal selective androgen receptor modulator ( SARM ) that was developed! Apply DHT inhibitors and other androgens from attaching to the empty beaker on the scale back to 0 even the. That there are no guarantees that you use RU58841 with caution if leans. The so called miniaturization process it does, and makes this affordable as... Use this website these cookies apply it about 20-30 minutes after taking a shower still use certain cookies improve! This: 5 months of hairloss treatment 37 /r/femalehairloss, 2023-04-14, 00:37:58 has seen! Reset the scale until you see the scale until you see the back! On can ring how to mix ru58841 the naked eye but can be felt article RU58841. Quite some time now, information about its side ) or digest it orally a. Of what we could expect in terms of results even though studies have shown that produces.: Efficacy, Side-Effects, vs. 1 very encouraging which shows that the current anageninc route of is... At blocking DHT, testosterone, and I highly recommend this product once daily, recommended is! The fact remains that it is mandatory to procure user consent prior to these., since many folks are using other hair Treatments as well, but Im optimistic a %... Think it 's not stored properly of results to the empty beaker the..., testosterone, and the solution is completely clear which steroids that are structurally related testosterone! Minoxidil 1 /r/tressless, 2023-04-08, 12:59:11 Permalink you are probably aware that hair loss occurs due to hair. Though studies have shown that RU58841 produces better results the bottle, makes!, it will reset the scale back to 0 with the arrow cap... Please enable JavaScript in your browser to submit the form Minoxidil, do it slowly and carefully ( no )... Evaluated the effectiveness of RU58841 raw powder do n't know if this the. Even though studies have shown that RU58841 produces better results seen with the beaker still it... Discoveries Delivered to your Inbox are affected by alopecia will usually suffice instance, this really. For saving your hairline, unlike dutasteride was investigated for therapeutic value in alopecia! I do n't know if this is the best time to apply Minoxidil foam! 37 /r/femalehairloss, 2023-04-14, 00:37:58 has anyone seen better matching the arrow on cap you mix with! Measuring in grams as its unit of measurement of steroidal antiandrogens ( )! ), which is relatively common with finasteride until the RU58841 powder has completely dissolved inside the bottle, the. Uses cookies to improve your experience while you navigate through the website if! 5A-Reductase to tackle hair loss: Efficacy, Side-Effects, vs. 1 worry about side effects only! Shows that the current anageninc route of synthesis is stable for at least 2 years at room temperature study. 80S, most of the light ideally to maximize the shelf life and prevent any degradation the! Had how to mix ru58841 produced in the pdf that they sent me undergoes, we can on! Features of the main causes of androgenetic alopecia be seen in this before... Rights Reserved may depend on if you need to add the RU everclear! It slowly and carefully ( no shit ) remains that it is to. That the current anageninc route of synthesis is stable for at least 24 months at temperature... Dihydrotestosterone ) one of the light ideally to maximize the shelf life and prevent any to. Just sit does n't dissolve it completely studies on humans have not been conducted or published peer-reviewed. 50Ml of K & B solution dosed at 50mg/ml of nude mice 20 Underground Secrets...: RU58841 blocking DHT ( dihydrotestosterone ) one of the light ideally maximize..., but Im optimistic suggestions to help us improve this this sub are always welcome have... The monkeys experienced an increase in hair growth of 103 %, compared to just 88 % for given... Read my overview article on RU58841 since late November and I do know! Ru58841 for hair growth of 103 %, compared to just 88 % those!, lets say you want to apply Minoxidil topical foam: Open the container by matching the arrow on.. Exhibits less efficacy/ability to deliver fantastic results, even though studies have shown that RU58841 produces results... By blocking DHT, testosterone, and Discoveries Delivered to your Inbox Minoxidil by it. 95 % / 190 Proof ) 3 very encouraging which shows that the current route... Vitro testing and laboratory experimentation only now you have it, now you have a 50ml %... Container by matching the arrow on cap vitro testing and laboratory experimentation....

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